Pre-implantation genetic testing for aneuploidy (PGT-A) is a screening test that can be done through the use of in vitro fertilization (IVF) where the embryos that are created can be tested for extra or missing chromosomes.
Chromosomes are string-like structures found in the centre (nucleus) of cells. A human cell typically has 46 chromosomes. An embryo receives 23 chromosomes from the sperm and 23 from the egg. Chromosomes are important because they contain the information that instructs the body’s cells how to function. Chromosomal aneuploidy in an embryo can result in failure of an embryo to implant, pregnancy loss or the birth of a child with a chromosome abnormality like Down syndrome.
The goal of PGT-A is to identify embryos with aneuploidy and choose to transfer an embryo that has the correct number of chromosomes. This generally gives you a higher chance that the specific embryo will implant in your uterus.